RHR: Reviewing the Evidence on the Serotonin Theory of Depression, with Dr. Joanna Moncrieff
In this episode, we discuss: The origins of the chemical imbalance theory of depression and whether there is scientific evidence to support this theory How human bias has perpetuated the myth of the serotonin theory and the use of tricyclic drugs to treat depression Our approach to understanding and treating depression prior to the chemical imbalance theory and how this theory has altered approaches to depression in the mental health profession Why the pharmaceutical industry sought to override the dominant conceptualization of depression Whether we can say that there is a true biological basis to depression What happens to people with and without depression when levels of neurotransmitters in the brain are altered in clinical trials and the role of the placebo effect in antidepressant drug trials The long-term negative effects of...