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RHR: Rediscovering Health, Nature, and Purpose-Driven Business, with Seth Spears

May 13, 2025
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In this episode, we discuss: The philosophy of conscious entrepreneurship Taking a healthier approach to dental care The importance of nature to physical and mental health Building resilience through nature and outdoor challenges The role of discomfort in health and growth Combating technology addiction and reclaiming human connection  Show notes: [embedded content] Hey everyone, Chris Kresser here. Welcome to another episode of Revolution Health Radio. This week, I’m excited to welcome Seth Spears as my guest. This will be a different conversation than I typically have on the show. Seth is a business strategist for conscious, purpose-driven entrepreneurs who value mission over margin and purpose over profit. He is an avid outdoors person himself. He’s started several companies in the past, some of which are certified B Corps. They all have a...

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RHR: How to Sharpen and Protect Your Mind for a Lifetime, with Dale Bredesen

April 29, 2025
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In this episode, we discuss: Revolutionizing Alzheimer’s prevention and early detection Blood testing and the four stages of cognitive decline Objective assessment tools for cognitive health Breakthrough results in clinical trials Essential lifestyle interventions: diet, exercise, and sleep The role of supplements and brain stimulation in Alzheimer’s prevention Show notes: [embedded content] Hey everybody, Chris Kresser here. Welcome to another episode of Revolution Health Radio. This week, I’m really excited to welcome Dr. Dale Bredesen back for his third appearance on the show. Many of you, I’m sure, have listened to the first two episodes or are familiar with Dr. Bredesen from other resources. He’s an internationally recognized expert in the mechanisms of neurodegenerative disease like Alzheimer’s and dementia. He graduated from Caltech, then earned his MD from Duke University. He served...

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Quality Matters: How to Choose and Use the Best Collagen Supplement

April 24, 2025
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Introduction If you’ve been paying attention to health and wellness trends, you’ve likely noticed collagen supplements everywhere—from your local health food store to your Instagram feed. It’s not just hype; the collagen market has grown to a nearly $3 billion global industry, and for good reason. Collagen is the most abundant protein in our bodies—it’s quite literally the stuff that holds us together. The word “collagen” comes from the Greek word “kólla” meaning glue, which perfectly describes its function as the structural framework for our skin, bones, tendons, and connective tissues. Our ancestors naturally consumed collagen-rich parts of animals—skin, tendons, and bone broths—as part of their nose-to-tail eating approach. Modern diets focused primarily on muscle meats have created a collagen gap that supplements can help address. This represents...

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Collagen: The Essential Building Block for Strong Joints and Bones

April 22, 2025
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The Foundation of Your Musculoskeletal System If you’ve ever winced going down stairs, felt that telltale morning stiffness, or worried about thinning bones, you’re likely experiencing what I see in my practice every day – the effects of declining collagen. I often tell my patients that collagen is literally the “glue” that holds us together – in fact, the word “collagen” comes from the Greek word “kólla” meaning glue. It’s the most abundant protein in your body, accounting for about 30% of your total protein content, and it’s absolutely crucial for maintaining the integrity of your joints, bones, and connective tissues. Think of collagen as the structural framework of your body – like the support beams in a house. Without enough of it, things start to sag,...

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RHR: Everything You Need to Know About Collagen

April 15, 2025
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In this episode, we discuss: What collagen is and why it matters Collagen for natural beauty: skin, hair, and nails Joint and bone health benefits of collagen Collagen’s Role in Muscle Recovery and Athletic Performance Collagen and gut health Improving sleep quality with collagen How to choose the right collagen supplement Cautions and considerations of collagen supplementation Show notes: “Effects of Oral Collagen for Skin Anti-Aging: A Systematic Review and Meta-Analysis” by Pu, et al. “Collagen Supplementation for Joint Health: The Link between Composition and Scientific Knowledge” by Martínez-Puig, et al. “Effect of collagen supplementation on knee osteoarthritis: An updated systematic review and meta-analysis of randomized controlled trials” by Simental-Mendía, et al. “Efficacy of undenatured collagen in knee osteoarthritis: Review of the literature with limited meta-analysis” by Kumar, et al.  “The Effects of Type I Collagen Hydrolysate Supplementation on...

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Collagen for Natural Beauty: The Science Behind Healthier Skin, Hair, and Nails

April 9, 2025
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That first moment you notice deepening lines around your eyes or suddenly realize your nails have become brittle and prone to breaking—these experiences often signal the same underlying issue: diminishing collagen. As we age, our bodies naturally produce less of this critical protein, but research shows that targeted supplementation can effectively restore many of those visible signs of youth. What Is Collagen and Why It Matters for Natural Beauty Collagen isn’t just any protein—it’s the most abundant protein in the human body, making up about 75-80% of your skin’s dry weight. [1] The word “collagen” comes from the Greek word “kólla,” meaning glue, which perfectly describes its function as the structural scaffolding that gives our skin its firmness and elasticity. [2] Our natural collagen production begins declining in...

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Bacillus coagulans: A Versatile and Safe Probiotic for Gut Health and Beyond

April 1, 2025
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If you’ve been following the latest developments in gut health research, you’ve likely encountered Bacillus coagulans. This unique probiotic has been gaining attention in the functional medicine community, and for good reason—the research supporting its benefits is already robust and continues to grow. As someone who’s worked with thousands of patients with gut issues, I’ve found that probiotics can sometimes be a double-edged sword. They offer tremendous benefits for many, but for others—particularly those with sensitive digestive systems—they can sometimes trigger discomfort. This is where B. coagulans offers a distinct advantage. What Is Bacillus coagulans? Bacillus coagulans is a spore-forming probiotic bacterium that stands apart from many of the more familiar lactic acid bacteria like Lactobacillus and Bifidobacterium. Its spore-forming ability gives it a remarkable resilience that most...

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Why Bacillus coagulans Is My Go-To Probiotic for IBS and SIBO

February 13, 2025
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If you’re struggling with irritable bowel syndrome (IBS) or small intestinal bacterial overgrowth (SIBO), you know how challenging these conditions can be to treat. The complex web of symptoms—abdominal pain, bloating, irregular bowel movements, and more—can significantly impact your quality of life. Studies show that IBS affects up to 15% of the global population, making it one of the most common gastrointestinal disorders worldwide [1]. When I first started my practice, I prescribed standard probiotics to my patients with IBS and SIBO, just like most clinicians. But I noticed something concerning: these patients not only didn’t improve—they often got worse. This observation sent me down a path of extensive research and clinical trial and error, ultimately leading me to discover that Bacillus coagulans was consistently the...

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RHR: Exploring Peak Health and Fitness, with Mark Sisson

February 11, 2025
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In this episode, we discuss: Mark’s journey from runner to fitness advocate The case against chronic cardio Footwear, biomechanics, and the importance of sensory input How to take a balanced approach to running Using a smarter strategy to optimize fitness The power of all-day movement   Show notes: [embedded content] Hey everybody. Chris Kresser here, welcome to another episode of Revolution Health Radio. This week I’m really happy to welcome back Mark Sisson as my guest. Mark is a legend in the ancestral health community. I’m sure most of you listening to this podcast know of Mark. He’s been an inspiration for many, including me. One of the first people I came across when I first started getting into the primal and paleo lifestyle. He’s the author of a number of best...

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RHR: Gut Health 3.0- The Power of Polyphenols and Postbiotics

January 14, 2025
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In this episode, we discuss: Gut Health 1.0: Probiotics and Bacillus coagulans Gut Health 2.0: Prebiotics and bacteriophages Gut Health 3.0: Polyphenols Gut Health 3.0: Postbiotics and butyrate The benefit of taking a synergistic approach to gut health A review of clinical case studies The future of gut health Show notes: “Bacillus coagulans MTCC 5856 supplementation in the management of diarrhea predominant Irritable Bowel Syndrome: a double blind randomized placebo controlled pilot clinical study” by Majeed, et al. “Evaluation of the stability of Bacillus coagulans MTCC 5856 during processing and storage of functional foods” by Majeed, et al. “Combined Supplementation of Inulin and Bacillus coagulans Lactospore Demonstrates Synbiotic Potential in the Mucosal Simulator of the Human Intestinal Microbial Ecosystem (M-SHIME®) Model” by Duysburgh, et al. “Probiotic characteristics of Bacillus coagulans and associated implications for human health and...

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